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Volume 26 - ICOP & ICPET 2020
ICOP & ICPET _ INPC _ ICOFS 2020, 26 - ICOP & ICPET 2020: 713-716 |
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Karimi Tar H, Ghasemi P, Hosseini M, Arefnia F, Hosseini S M, Zibaii M I et al . Design and Fabrication a Wireless Implantable LED Illumination System for Optogenetic Applications. ICOP & ICPET _ INPC _ ICOFS 2020; 26 :713-716
URL: http://opsi.ir/article-1-2164-en.html
URL: http://opsi.ir/article-1-2164-en.html
Hedieh Karimi Tar1 , Purya Ghasemi1 , Mohammad Hosseini1 , Fatemeh Arefnia1 , Seyedeh Mahshad Hosseini1 , Mohammad Ismail Zibaii * 1, Leila Dargahi1
1- Shahid Beheshti University
Abstract: (1684 Views)
Optogenetics as a new tools in neuroscience provides an effective way of manipulating a specific cell type by light stimulating microbial opsin expressed cells on a timescale of milliseconds. Typically, light delivery into targeting areas is achieved using optical fibers coupled to external laser diodes or light emitting diodes (LEDs). Also, those laser diodes require high electrical power, which is an obstacle to achieve wireless operation of implanted device. In this article, we report development of an implantable wireless optogenetic device with a radio-frequency (RF) power source and controller, this implant produces sufficient light (473 nm) power for optogenetic stimulation. The RF frequency of 480 kHz can accommodate transmission distance up to 30 cm between the RF generator and the receiver loop antenna. This technology opens the door for optogenetic experiments in which animals are able to behave naturally with optogenetic manipulation.
Keywords: Implantable LED, RF frequency, Neuroscience, Optical stimulation, Optogenetic, Wireless system.
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