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Sadegh N, Khadem H, Tavassoli H. Fluorescence Suppression in Raman Spectroscopy Using Photobleaching Method for Pharmaceutical Samples. ICOP & ICPET _ INPC _ ICOFS 2014; 20 :1489-1492
URL: http://opsi.ir/article-1-129-en.html
URL: http://opsi.ir/article-1-129-en.html
1- Shahid Beheshti University
Abstract: (9344 Views)
in this article we offered a method for improving the ratio of signal to fluorescence in Raman spectroscopy based on photobleaching. It was demonstrated to be a simple approach to remote reduction and suppression the magnitude of the fluorescent background reduced exponentially with time. Pre-exposure to laser light significantly reduces sample autofluorescence, but minimally affects Raman signals. We demonstrated the capability of this method for Raman spectral measurements of acetaminophen tablets.
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