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Meydanloo S, Haghjoo R, Farhangi Y, S.Reihani S. Formation of Spherical Vesicles by Electro-formation and considering endocytosis and exocytosis process on them by using optical tweezers. ICOP & ICPET _ INPC _ ICOFS 2014; 20 :1645-1648
URL: http://opsi.ir/article-1-45-en.html
URL: http://opsi.ir/article-1-45-en.html
1- Institute for Advanced Studies in Basic Sciences in Zanjan
2- Sharif University of Thechnology
2- Sharif University of Thechnology
Abstract: (6249 Views)
In this paper the designing and fabricating procedure of electro-formation device to produce spherical phospholipid vesicles, is presented. The hydrophobic property of the tail of phospholipid molecules and the hydrophilic head of them form some self-assemble structures in polar solutions. By applying different alternative sinusoidal electrical fields, the optimum frequency and voltage for producing vesicles from a few microns to several ten microns, is obtained. In next step by using optical tweezers, micron size particle was forced inside the vesicle. This process is called endocytosis and in biological cells the force for this process is provided by proteins.
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