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year 28, Issue 2 (ICOP & ICPET 2022 2022)
ICOP & ICPET _ INPC _ ICOFS 2022, 28(2): 578-581 |
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ghasemi P, zibaii M I, Hosseini S M, Salehi Moghadam M R. Design and fabrication of electrophysiology recording system based on optoelectrode array for in vitro optogenetics applications.. ICOP & ICPET _ INPC _ ICOFS 2022; 28 (2) :578-581
URL: http://opsi.ir/article-1-2646-en.html
URL: http://opsi.ir/article-1-2646-en.html
Pouria Ghasemi *1 
, Mohammad ismail Zibaii1 , Seyedeh Mahshad Hosseini1 , Mohammad Reza Salehi Moghadam1
, Mohammad ismail Zibaii1 , Seyedeh Mahshad Hosseini1 , Mohammad Reza Salehi Moghadam1
1- Shahid Beheshti University
Abstract: (718 Views)
In the optogenetic technique, which studies the neural system with light, it is necessary to examine cell
function at the same time or after light stimulation using electrophysiological recording methods. In this paper, an
integrated array optrode system for optical stimulation and electrophysiology recording is designed and fabricated
for optogenetic applications. In this system using micromachining and pholithogeraphy a 4 × 4 microelectrode
array was fabricated with circular diameter 300 μm from and impedance 104 KΩ at 1 kHz. In this design, LEDs
with dimensions of 1 × 0.5 × 0.35 mm, wavelength of 473 nm and a maximum radiant power of 60 mW have been
used for irradiation. The performance of the designed system has also been evaluated by measuring the pc12 nerve
signal and cardiac stem cells.
Type of Study: Experimental |
Subject:
Special
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