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Abdolhosseinzadeh Namini M, Jala-Kamali M. The Effect of Charge Transfer Processes on Photodynamic Therapy Mechanism. ICOP & ICPET _ INPC _ ICOFS 2014; 20 :1309-1312
URL: http://opsi.ir/article-1-261-en.html
URL: http://opsi.ir/article-1-261-en.html
Abstract: (15793 Views)
Photodynamic therapy is an effective treatment for a variety of tumors and skin diseases. In this paper, the study of the charge transfer processes, the generation of free radicals and their impact on cell death and total efficiency of photodynamic therapy is made possible by completing the previous dynamic models that only describe the energy transfer processes and the generation of reactive oxygen in photodynamic therapy. In the present model the concentration of molecules involved in these processes was studied as a function of time by considering the rate equations. The results show that although the energy transfer processes have a significant impact on total efficiency of Photodynamic therapy, but we can’t ignore the effect of charge transfer processes on total efficiency.
Keywords: Photodynamic Therapy, Photosensitizer, Charge Transfer, Energy Transfer, Mathematical Modeling
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