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year 27, Issue 2 (ICOP & ICPET 2021 2021)                   ICOP & ICPET _ INPC _ ICOFS 2021, 27(2): 687-691 | Back to browse issues page

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Amini M, Pedram M M, Gharibzadeh S, Ouchani M. Modeling of Krichmann plasmonic sensor for early detection of Alzheimer's diseases utilizing amyloid beta (Ab) and tau protein structures. ICOP & ICPET _ INPC _ ICOFS 2021; 27 (2) :687-691
URL: http://opsi.ir/article-1-2457-en.html
Modeling of Krichmann plasmonic sensor for early detection of Alzheimer's diseases utilizing amyloid beta (Ab) and tau protein structures
Morteza Amini *1 , Mir Mohsen Pedram2 , Shahriyar Gharibzadeh3 , Mahshad Ouchani4
1- Department of Cognitive Modeling, Institute for cognitive science studies, Shahid Beheshti University
2- Department of Cognitive Modeling, Institute for cognitive science studies, Shahid Beheshti University, Department of Electrical and Computer Engineering, Faculty of Engineering, Kharazmi University
3- Department of Cognitive Modeling, Institute for Cognitive and Brain Science, Shahid Beheshti University
4- Department of Cognitive Neuroscience (Brain and Cognition), Department of Cognitive Neuroscience, Institute for Cognitive and Brain Science, Shahid Beheshti University
Abstract:   (910 Views)

In this paper, a plasmonic sensor for early detection of Alzheimer's is proposed. The proposed sensor structure is in the form of Kirchmann and is provided by fixing the structural properties of Alzheimer's including amyloid beta (Ab) and tau protein on a grid on the analyte sensor. In this design, a similar finite difference time domain (FDTD) method is used to analyze the results. Important sensor parameters have been calculated to evaluate the Alzheimer's sensor. The sensitivity, competency criteria and quality coefficient calculated for this sensor are refractive index 1200 nm / RIU, 241.66 RIU-1 and 242.83, respectively, which indicates an improvement in the proposed structure compared to the previously proposed early detection Alzheimer's sensors.

Keywords: Plasmonic sensor, Alzheimer's sensors, amyloid beta (Ab), Tau protein
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Type of Study: Research | Subject: Special
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