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year 27, Issue 2 (ICOP & ICPET 2021 2021)
ICOP & ICPET _ INPC _ ICOFS 2021, 27(2): 21-24 |
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G. Shemirani M, Hoseini S, Godarzi A, Esmaeilpour M, Mohammadimasoudi M, Shahsavarani H, et al . Distinguish normal cells from cancer cells based on transmission spectroscopy. ICOP & ICPET _ INPC _ ICOFS 2021; 27 (2) :21-24
URL: http://opsi.ir/article-1-2296-en.html
URL: http://opsi.ir/article-1-2296-en.html
M G. Shemirani1 
, Sadi Hoseini2 , Ali Godarzi1 , Mahbobe Esmaeilpour1 , Mohammad Mohammadimasoudi *1 , Hosein Shahsavarani3 , Ezeddin Mohajerani4 , Javad Koohsorkhi1
, Sadi Hoseini2 , Ali Godarzi1 , Mahbobe Esmaeilpour1 , Mohammad Mohammadimasoudi *1 , Hosein Shahsavarani3 , Ezeddin Mohajerani4 , Javad Koohsorkhi1
1- University of Tehran, Faculty of New Sciences and Technologies
2- Laboratory of Regenerative Medicine and Biomedical Innovations, Pasteur Institute of Iran, Tehran, Iran
3- Laboratory of Regenerative Medicine and Biomedical Innovations, Pasteur Institute of Iran, Tehran, Iran, Department of Cellular and Molecular Sciences, Faculty of Bioscience and Biotechnology, Shahid Beheshti University, Tehran, Iran
4- 4Shahid Beheshti University, Laser & Plasma Institute
2- Laboratory of Regenerative Medicine and Biomedical Innovations, Pasteur Institute of Iran, Tehran, Iran
3- Laboratory of Regenerative Medicine and Biomedical Innovations, Pasteur Institute of Iran, Tehran, Iran, Department of Cellular and Molecular Sciences, Faculty of Bioscience and Biotechnology, Shahid Beheshti University, Tehran, Iran
4- 4Shahid Beheshti University, Laser & Plasma Institute
Abstract: (1115 Views)
Simultaneous microscopic imaging and a spectroscopy of biological cell in vitro environment are applied to distinguish between normal cell and cancer cell. The region of spectroscopy is between 480 to 640 nm. Breast cancer cells (MCF-7), hamster ovary cells (Cho) and mesenchymal stem cells are investigated. Hamster ovary cells and the mesenchymal stem cells can be distinguished from cancer cells by analyzing the experimental data with Boltzmann mathematical functions. This method is reproducible and cost-effectiveness. The method can be used as an alternative In-vitro assay to detect cancer cells.
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