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Volume 26 - ICOP & ICPET 2020
ICOP & ICPET _ INPC _ ICOFS 2020, 26 - ICOP & ICPET 2020: 605-608 |
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Asadollahi A, Rezaei A, Latifi H. Design and Construction of Photoacoustic Microscopy System for 3D Imaging of Brain. ICOP & ICPET _ INPC _ ICOFS 2020; 26 :605-608
URL: http://opsi.ir/article-1-2130-en.html
URL: http://opsi.ir/article-1-2130-en.html
1- Laser and Plasma Research Institute, Shahid Beheshti University
Abstract: (1592 Views)
3D Imaging of brain is important in many aspects such as studying structure and hemodynamics in cognitive science. In this study, we designed and constructed a 3D Photoacoustic imaging system called Acoustic-Resolution Photoacoustic Microscopy (AR-PAM). Advantages of the Photoacoustic imaging are high contrast and depth of imaging with acceptable resolution which was impossible before by existing imaging modalities. In this imaging system we used a nanosecond pulsed Nd:YAG laser for illumination of the sample and an ultrasonic transducer for Photoacoustic (PA) waves detection. Tests were done on an exposed cortex of rat brain. Imaging results show that resolution of the system is less than 50um at the depth of about 3 mm.
Keywords: Photoacoustic (PA) wave, Acoustic-Resolution Photoacoustic Microscopy (AR-PAM), Nanosecond Pulsed Laser, Ultrasonic Transducer
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