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Volume 26 - ICOP & ICPET 2020
ICOP & ICPET _ INPC _ ICOFS 2020, 26 - ICOP & ICPET 2020: 557-560 |
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Seyed Nazari M H, Ghasemi P, Hosseini S M, Arefnia F, Fahanik Babaei J, Eliassi A et al . Controlling of Current Across Lipid Membranes using Laser-Induced Gold Nanoparticle Heating. ICOP & ICPET _ INPC _ ICOFS 2020; 26 :557-560
URL: http://opsi.ir/article-1-2119-en.html
URL: http://opsi.ir/article-1-2119-en.html
Mir hossein Seyed Nazari1 
, Pouria Ghasemi1 , Seyedeh Mahshad Hosseini1 , Fatemeh Arefnia1 , Javad Fahanik Babaei1 , Afsaneh Eliassi1 , Mohammad Ismail Zibaii * 1
, Pouria Ghasemi1 , Seyedeh Mahshad Hosseini1 , Fatemeh Arefnia1 , Javad Fahanik Babaei1 , Afsaneh Eliassi1 , Mohammad Ismail Zibaii * 1
1- Shahid Beheshti University
Abstract: (1554 Views)
In this paper, we used temperature manipulation a bilayer lipid membrane (BLM) to reversibly control the electrical resistance and the amount of current that flows through the bilayer membrane with pA resolution. For this experiment, heating is achieved by irradiating AuNPs that are surrounded by the bilayer membrane with laser light at their plasmon resonance frequency. Obtained results show that the AuNPs convert light into local heating, creating small and localized heat sources, lead to the formation of a small pore in the lipid membrane and ultimately allowing increasing the permeability of BLMs. The whole process is monitored with bright field microscopy and patch-clamp equipment. This approach of controlling biological systems and cellular function with high Spatio-temporal resolution can be used for neuronal photostimulation.
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