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Volume 25 - ICOP & ICPET 2019                   ICOP & ICPET _ INPC _ ICOFS 2019, 25 - ICOP & ICPET 2019: 229-232 | Back to browse issues page

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Baloochi A, Bigdeli M R, Dargahi L, Nazari S M, Ghorbani A, Chavoshinezhad S, et al . Prevention of Stroke in Rats Using Optogenetic Technique . ICOP & ICPET _ INPC _ ICOFS 2019; 25 :229-232
URL: http://opsi.ir/article-1-1905-en.html
1- Shahid Beheshti University, Tehran
Abstract:   (1823 Views)
Brain Stroke is one of the most dangerous diseases of the nervous system. This complication is the second leading cause of death in the world. Different methods have been suggested for the treatment of this disease. In this study, we study the preventive effects of optogenetics stimulation in the animal model of ischemic stroke. For this purpose, by injection of Channelrhodopsin (CHR) opsin, implantation of optical fibers and laser blue light irradiation in the rat striatum, glutamateuric neurons were stimulated. Obtained results show optical stimulation leads to increasing of neurogenesis in the SVZ region and thereby reducing the infract volume after induction of ischemic stroke.
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Type of Study: Research | Subject: Special

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