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ICOP & ICPET 2018, 24 - : 209-212 Back to browse issues page
Design and fabrication a motorized Microdrive optrode for single-unit recording for optogenetics applications
Mahnaz Asadolah Salmanpour * 1, Mohammad Ismail Zibaii 1, Hamid Latifi 1, Abbas Haghparast 2, Leila Dargahi 2, Abdolaziz Ronaghi 2, Zahra Fatahi 2
1- Laser and Plasma Research Institute, Shahid Beheshti University
2- Neuroscience Research Center, Shahid Beheshti University of Medical Sciences
Abstract:   (597 Views)
In order to use an optogenetic technique for controlling closed-loops of neurological diseases, it is necessary to design and fabricate an implantable optrode as an optical and electrical system for simultaneous optical stimulation and electrical recording from neural. Microdrive is electrical and optical system that fix on the rat skull and can be used to record neural activity without disturbing the behavior of the animal. It can also be used optical fiber for optical stimulation simultaneously, so it can be used as optrode in closed-loop control systems for neurological diseases based on optogenetic technique. In this paper, an optrode based on motorized microdrive was designed and fabricated. It was used for in-vivo single unit recording in an anesthetized rat.
Keywords: Optogenetics, optrode, motorized microdrive, single-unit recording, Neuron.
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Type of Study: Research | Subject: Special
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Asadolah Salmanpour M, Zibaii M I, Latifi H, Haghparast A, Dargahi L, Ronaghi A et al . Design and fabrication a motorized Microdrive optrode for single-unit recording for optogenetics applications. ICOP & ICPET. 2018; 24 :209-212
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انجمن اپتیک و فوتونیک ایران Optics and Photonics Society of Iran
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