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Asadolah Salmanpour M, Zibaii M I, Latifi H, Haghparast A, Dargahi L, Ronaghi A et al . Design and fabrication a motorized Microdrive optrode for single-unit recording for optogenetics applications. ICOP & ICPET _ INPC _ ICOFS 2018; 24 :209-212
URL: http://opsi.ir/article-1-1454-en.html
URL: http://opsi.ir/article-1-1454-en.html
Mahnaz Asadolah Salmanpour * 
1, Mohammad Ismail Zibaii1 , Hamid Latifi1 , Abbas Haghparast2 , Leila Dargahi2 , Abdolaziz Ronaghi2 , Zahra Fatahi2
1, Mohammad Ismail Zibaii1 , Hamid Latifi1 , Abbas Haghparast2 , Leila Dargahi2 , Abdolaziz Ronaghi2 , Zahra Fatahi2
1- Laser and Plasma Research Institute, Shahid Beheshti University
2- Neuroscience Research Center, Shahid Beheshti University of Medical Sciences
2- Neuroscience Research Center, Shahid Beheshti University of Medical Sciences
Abstract: (2464 Views)
In order to use an optogenetic technique for controlling closed-loops of neurological diseases, it is necessary to design and fabricate an implantable optrode as an optical and electrical system for simultaneous optical stimulation and electrical recording from neural. Microdrive is electrical and optical system that fix on the rat skull and can be used to record neural activity without disturbing the behavior of the animal. It can also be used optical fiber for optical stimulation simultaneously, so it can be used as optrode in closed-loop control systems for neurological diseases based on optogenetic technique. In this paper, an optrode based on motorized microdrive was designed and fabricated. It was used for in-vivo single unit recording in an anesthetized rat.
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