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navaeipour F, tajalli H, rashidi M R, mollabashi M, ranjbari F, afsharan H. The effect of laser parameters on photodynamic therapy by Zinc Phthalocyanine. ICOP & ICPET _ INPC _ ICOFS 2015; 21 :809-812
URL: http://opsi.ir/article-1-788-en.html
URL: http://opsi.ir/article-1-788-en.html
Farzaneh Navaeipour * 1, Habib Tajalli2 , Mohammad reza Rashidi3 , Mahmoud Mollabashi1 , Farideh Ranjbari3 , Hadi Afsharan1
1- Iran University of Science and Technology
2- tabriz university
3- Tabriz University of Medical Sciences
2- tabriz university
3- Tabriz University of Medical Sciences
Abstract: (3823 Views)
In this paper we have used photodynamic therapy for destruction of cancer cells. The Zinc Phthalocyanine (ZnPc) has been used as a photosensitizing drug and a laser diode with λ= 675 nm as a light source. The light irradiation on Zinc Phthalocyanine produses reactive oxygen species (ROS) that destroy the cancerous tissue. The cancer cells in the presence of various concentrations of drug, were irradiated by laser with various powers and irradiatin times. It was found that, laser with a power of 80 mW and exposure time of 60 seconds has the best efficiency of destruction of cancer cells.
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