%0 Journal Article %A Shokoufi, Nader %A Abbasi Ahd, Atefeh %A Kargosha, Kazem %T Photo Thermal Lens Spectrometry of Gold Nanoparticles Interaction with Thiol Containing Biomolecules %J Accepted and Presented Articles of OPSI Conferences %V 21 %N 0 %U http://opsi.ir/article-1-794-en.html %R %D 2015 %K biomolecules, gold nanoparticles, Photothermal lens microscopy, Plasmonic, %X Sensitivity, thermooptical properties and low sample consumption are major properties that highlighted Photo Thermal Lens microscopy (PTLM) for detection of biomolecules. In this work, we utilized a coaxial photo thermal lens microscope equipped with a continuous-wave excitation (wavelength, 532 nm) and probe (wavelength, 652 nm) laser beam to investigate the interactions of gold nanoparticles with Captopril as an example of thiol containing biomolecules. GNPs due to their surface plasmon resonance (SPR) possess the absorption in visible range. Following the addition of trace Captopril, the color of gold colloid solution gradually changes. As a consequence the Photothermal lens signal enhanced. The changes of PTLM signal were found to be proportional to the concentration of Captopril over the range of 0.1–2 mgL−1. %> http://opsi.ir/article-1-794-en.pdf %P 1603-1606 %& 1603 %! %9 Research %L A-10-1-774 %+ Chemistry & Chemical Engineering Research Center of Iran (CCERCI) %G eng %@ 1126-3278 %[ 2015