TY - JOUR T1 - Formation of Spherical Vesicles by Electro-formation and considering endocytosis and exocytosis process on them by using optical tweezers TT - ساخت آبدانک های کروی به روش الکتروفرمیشن و بررسی فرایند برون رانی و بیگانه خواری غشا با استفاده از انبرک نوری JF - opsi JO - opsi VL - 20 IS - 0 UR - http://opsi.ir/article-1-45-en.html Y1 - 2014 SP - 1645 EP - 1648 KW - Electro-formation KW - ITO coverslips KW - Optical tweezers KW - Phospholipid Vesicles N2 - In this paper the designing and fabricating procedure of electro-formation device to produce spherical phospholipid vesicles, is presented. The hydrophobic property of the tail of phospholipid molecules and the hydrophilic head of them form some self-assemble structures in polar solutions. By applying different alternative sinusoidal electrical fields, the optimum frequency and voltage for producing vesicles from a few microns to several ten microns, is obtained. In next step by using optical tweezers, micron size particle was forced inside the vesicle. This process is called endocytosis and in biological cells the force for this process is provided by proteins. M3 ER -