TY - JOUR T1 - Design and fabrication a motorized Microdrive optrode for single-unit recording for optogenetics applications TT - طراحی و ساخت اپتورود بر پایه میکروجابه جاگر موتوردار جهت ثبت سیگنال تک واحدی نورون برای کاربردهای اپتوژنتیک JF - opsi JO - opsi VL - 24 IS - 0 UR - http://opsi.ir/article-1-1454-en.html Y1 - 2018 SP - 209 EP - 212 KW - Optogenetics KW - optrode KW - motorized microdrive KW - single-unit recording KW - Neuron. N2 - In order to use an optogenetic technique for controlling closed-loops of neurological diseases, it is necessary to design and fabricate an implantable optrode as an optical and electrical system for simultaneous optical stimulation and electrical recording from neural. Microdrive is electrical and optical system that fix on the rat skull and can be used to record neural activity without disturbing the behavior of the animal. It can also be used optical fiber for optical stimulation simultaneously, so it can be used as optrode in closed-loop control systems for neurological diseases based on optogenetic technique. In this paper, an optrode based on motorized microdrive was designed and fabricated. It was used for in-vivo single unit recording in an anesthetized rat. M3 ER -