In closed loop optogenetics controlling of the neural system, for treatment of neurological diseases it should be used online neural signal processing. To investigation of optogenetics effects on the neural system or closed loop controlling, neuroscientists study the animal behavior or signal recording from the target area. One of the important brain signal recording is single-unit recording. In this paper, an algorithm is proposed to online spike detection and sorting them in single unit recording based on wavelet transform. This algorithm is programmed by Labview software and raw data is processed. Since it has a high processing speed and its simplicity, this algorithm can be run in a personal PC and can be used for studying and controlling the neural network system with closed loop optogenetics technique. This processing system is using at optogenetics group of Shahid Beheshti university for studying of some diseases such as addiction, seizer and autism.

Keywords: Closed loop controlling, Optogenetics, single unit recording, wavelet transform

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